It is worth noting that endothelial cell‐specific knockout of Cav1 or Cavin1 respectively could directly induce PAH in C57 mice,18, 19 and CAV1 is a well‐known mutant gene in idiopathic pulmonary artery hypertension (IPAH) patients.20 This evidence concerns the gene CAV1 and idiopathic pulmonary arterial hypertension.