CTH and HIV infectious disease: In addition, abnormalities in CTH and SD were found correlations with cognitive attention and motor functions, which were reported disruption in early HIV infection and related to nigrostriatal pathways and prefrontal–subcortical circuitry (Chang, Ernst, Leonido‐Yee, & Speck, 2000; Everall, Luthert, & Lantos, 1991; Goodkin et al., 2017).