Since synthetic agomir for miR-378* (AgomiR-378*) transfection could not affect the mRNA expression of CYP7B1, CYP8B1, and CYP27A1, we speculated that miR-378 but not miR-378* contributes to the effect of Ad-378 infection on the expression of these enzymes (Figure S2C). The gene discussed is CYP8B1; the disease is infection.