CYP27A1 and infection: Given that the hepatic expression of CYP7B1, CYP8B1, and CYP27A1 but not CYP7A1 was increased by Ad-378 infection, the increased BA levels in the bile of gallbladders implies that miR-378 overexpression might enhance the conversion of cholesterol to BAs through CYP7B1, CYP8B1, and CYP27A1, but not CYP7A1.