36. Consistent with these studies, we show that circ1662 is positively correlated with YAP1 in CRC. Overexpressed circ1662 promotes YAP1 protein transport to the nucleus and reduces the YAP1 protein level in the cytoplasm. Moreover, circ1662 overexpression decreases the level of p-YAP1, which cannot be transported into the nucleus 37. This evidence concerns the gene YAP1 and colorectal carcinoma.