After stimulation, the percentage of C02-Activated-IFNG and C06-Activated-IL2RA of TCR-TMART-1 was downregulated, while the fragment of C01-Activated-CD69, C11-Activated-IL15, and C12-Cytotoxic-GNLY was upregulated with increased tumor PD-L1 levels (Figure 3B). This evidence concerns the gene GNLY and neoplasm.