Among these genes, we found that PHB2 changed remarkably in HCC cells with PINT87aa, FOXM1, or PINT87aa+FOXM1 overexpression compared with vector-transfected cells (Figure 6A), as well as in senescent HCC cells compared with proliferating HCC cells (Figure S5B). This evidence concerns the gene FOXM1 and hepatocellular carcinoma.