CX3CL1 and non-small cell lung carcinoma: To examine this hypothesis, we detected the content of CX3CL1 in vertebral cancellous bone and vertebral bone marrow endothelial cells (VBMECs), determined whether CX3CL1 influenced the biological behaviors of circulating NSCLC cells, such as adhesion, transendothelial migration, and invasion, and investigated the underlying mechanisms.