Considering that HBO1 is upregulated in several other human cancers (gastric cancer, bladder cancer, etc.)22, 23, 33 and functions as a potential oncogene 22, 23, 33, it certainly will be interesting to further test the potential anti-cancer activity of HBO1 genetic silencing or pharmacological inhibition in other cancer models. Here, KAT7 is linked to urinary bladder cancer.