Of these three HOXA-AS2-targeted drugs used in AML, carmustine is a broad-spectrum anticancer drug with good curative effect in patients with Hodgkin's disease 56 and AML 57, 58, as well as some curative effect in patients with breast cancer 59, lung cancer 60, brain cancer 61, 62 and brain metastasis 63, 64. The gene discussed is HOXA-AS2; the disease is lung carcinoma.