KIF23 and colorectal carcinoma: The results suggested that the levels of KIF23 mRNA in unpaired CRC tumors (N=380) were significantly upregulated compared with those in normal colorectal tissues (N=51) (P<0.001, Fig. 1A), and the upregulation of KIF23 in colorectal cancer was further confirmed in paired tumors and adjacent normal tissues (N=32, P<0.001, Fig. 1B).