Among the 62 GBC tissue samples, 43.55% (27/62) of cases were strong stained, 22.58% (14/62) of cases were medium stained, 33.87% (21/62) of cases were weak or negatively stained, the opposite of that only 6.67% (2/30) of the cholecystitis tissues showed strong staining of ARRB1 protein (Figure 1 B). This evidence concerns the gene ARRB1 and Cholecystitis.