Serum transfer experiments showed that LTβR−/− mice treated with immune serum exhibit significantly prolonged survival (up to day 14 p.i.)compared to littermates that received control serum, which died by day 11 p.i. IFN-γR−/− mice served as infection controls and succumbed as reported around day 8 p.i. (53). This evidence concerns the gene IFNGR1 and infection.