LTBR and infection: In WT mice, the parasite burden rose only moderately, while LTβR−/− mice showed a significant increase by day 10 p.i. as well as significantly larger amounts on days 7 and 10 p.i. To summarize, LTβR−/− mice showed increased parasite burden compared to WT mice, pointing toward a failure of these animals to adequately control parasite proliferation in the acute phase of infection.