These cells produce distinct cytokines in response to infection, such as interleukin-12 (IL-12) and TNF, thus activating and stimulating other cell types, including NK cells (18), T cells (19), innate lymphoid cells (ILCs) (20), and macrophages (21), which in turn, produce inflammatory cytokines such as IFN-γ. This evidence concerns the gene TNF and infection.