LTBR and infection: In infection models, LTβR−/− mice show pronounced defects in their immune response against Listeria monocytogenes, Mycobacterium tuberculosis (5), cytomegalovirus (9), lymphocytic choriomeningitis virus (LCMV) (10), and Zika virus (11), as well as Toxoplasma gondii (T. gondii) (12).