In regard to immune cells, Mei and colleagues examined a group of CIDP patients, all of which presented with dominant motor involvement, and reported an upregulation of IL-17, IL-8, and IL-6 prior to the beginning of IVIg treatment and a downregulation of IL-4, IL-5, and IL-7 (Th2 cytokines) after an examination of 16 cytokines in CIDP patient CSF [117]. Here, IL4 is linked to chronic inflammatory demyelinating polyradiculoneuropathy.