In HIV- women, DNA methylation at CpGs -3400 within the ADIPOQ promoter correlated with higher glucose and lower serum adiponectin concentrations, which is consistent with findings from Bouchard et al. who similarly reported an association between ADIPOQ methylation and hyperglycemia and circulating adiponectin concentrations during pregnancy [49]. This evidence concerns the gene ADIPOQ and Hyperglycemia.