Moreover, EPC cells cotransfected with bmp8a expressing plasmid and IFNφ1, IFNφ3, or EPC IFN promoter-driven luciferase plasmid, followed by infection with or without GCRV, had markedly increased intracellular IFNφ1, IFNφ3, or EPC IFN promoter-driven luciferase activities (Fig. 2q–s). The gene discussed is BMP8A; the disease is infection.