In line with these observations, both flight and ground infections led to the upregulation of transcripts encoding several chemokines important for recruiting neutrophils and other immune cells to the site of infection, including CXCL1, CXCL2, CXCL3, CXCL8, and CCL20. NFKBIZ encodes NF-κB inhibitor zeta (IκBζ), which both represses and activates select NF-κB genes60. This evidence concerns the gene CXCL8 and infection.