Notably, the protocadherin gamma cluster contains one of the previously known 25 pan-tissue DS genes (PCDHGA2) [2], and differential methylation within the cluster has been observed in diverse DS tissues, which include fetal brain, adult brain, neonatal blood, T-lymphocytes, buccal epithelial cells, and placenta [29–31, 33–35]. The gene discussed is PCDHGA2; the disease is Dravet syndrome.