MAPK8 and metabolic dysfunction-associated steatohepatitis: To determine whether LncRNA-gm9795 up-regulates the inflammatory factors by activating NF-kB/JNK signaling pathway through ERS, after interfering with LncRNA-gm9795, MCD+LPS and PA were used to establish NASH models, and endoplasmic reticulum stress agonist Thapsigargin (Tg) (800 nM, as the dosage recommended in the instructions) was added to stimulate the models for 24h.