The accumulation of a variety of inflammatory cytokines (such as TNF\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\alpha {}$$\end{document}α, IL-1, IL-6, etc.)causes liver inflammation and liver cell damage, and then progresses to liver fibrosis [25]. Here, IL1B is linked to Hepatic fibrosis.