The correlation between GLUT-1 and FDG uptake was found in multiple malignancies such as breast cancer [22], lung cancer [23], cervical cancer [24], pancreatic cancer [25] and colorectal cancer [12] et al. However, Ran Hong’s study show that the GLUT-1 expression was not associated with FDG uptake, the discrepancy between two studies may be caused by differences in FDG parameters, only one radio-parameter was included in Ran Hong’s research [26]. This evidence concerns the gene SLC2A1 and colorectal cancer.