While many of the known key players of breast cancer, such as BRCA1, ERBB2, ESR1, GATA3, CDH1, FOXA1, were frequently identified as rCCS genes by CLIP (Dataset EV13), we also observed novel genes, such as ECHDC1, SYCP2, GPX1, and MSN, whose role in breast cancer have not yet been studied extensively (Dataset EV13). Here, ESR1 is linked to breast cancer.