In line with the mutual exclusivity property of many SL partners (Unni et al,2015; Varmus et al,2016), we also found that endometrial tumors harboring loss‐of‐function PTEN mutations had much lower expression levels of DDX27 (Fig 6H, P = 1.29 × 10−21, Wilcoxon test), and this property was also significant in the TCGA Pan‐Cancer dataset (Appendix Fig S18D, P = 1.06 × 10−19). This evidence concerns the gene DDX27 and endometrium neoplasm.