When comparing PD-L1 expressions on TAMs in these tumor samples to the Smofl/fl controls, we found that SmoCM had the highest PD-L1 expression (P < 0.05) and Stat3ΔM and SmoCMStat3ΔM had the lowest expressions (P < 0.005) of PD-L1 with no significant difference between the 2 groups (Figure 7E). This evidence concerns the gene CD274 and neoplasm.