As patients presenting with a clearly recognizable macular dystrophy phenotype (including those associated with variants in ABCA4, PRPH2, RS1, BEST1) and X‐linked rod‐cone dystrophy/Choroideremia (RPGR, RP2, CHM) were investigated by alternative pathways, the diagnostic yield of NGS176 for all patients with IRD is likely to be significantly higher than we report. The gene discussed is PRPH2; the disease is choroideremia.