Accelerated long‐term forgetting, in which memory impairment becomes apparent over 7‐day to 3‐month retention intervals, is also identified as an early presymptomatic feature of subtle cognitive dysfunction in familial AD individuals10, 11 and ApoE ε4 carriers12, 13 whose performance on standard short‐term memory testing is still intact. This evidence concerns the gene APOE and memory impairment.