The association of CTLA-4 polymorphisms with the risk to develop T1DM has been investigated in different populations with conflicting data.8Recent study has shown no association between the aforementioned SNPs and susceptibility toT1DM among Sudanese adults.9Since Sudanese population is characterized by multiethnic groups, the search for further association between groups of different age and ethnicity could likely help pursuing conclusive remarks about this association. Here, CTLA4 is linked to type 1 diabetes mellitus.