CD3D and cervical squamous cell carcinoma: By performing univariate and LASSO Cox regression analyses, three hub IRGs (CD3E, CD3D, and LCK) were selected to establish an immune-related prognostic signature for CESC patients, where the AUC values of 1-, 3-, and 5-year OS were 0.705, 0.641, and 0.662 in the training group, and 0.767, 0.770, and 0.702 in the testing group and 0.651, 0.648, 0.612 in the external validation, respectively, indicating the reliably predictive capacity for CESC patient prognosis.