We constructed a 15-ferroptosis mRNA signature for predicting the prognosis of ovarian cancer, composed of CDKN1B, CXCR4, FAS, FOS, FOXO1, GABARAPL1, HDAC1, IFNG, IL24, MTMR14, NFKB1, PEX3, PPP1R15A, RB1, and SIRT2. Here, PPP1R15A is linked to ovarian cancer.