PML and acute promyelocytic leukemia: 95% of APL have t(15;17) (de Thé et al., 1990; Kakizuka et al., 1991) chromosomal translocations generating promyelocytic leukemia/retinoic acid receptor α (PML/RARα) fusion genes (Kitareewan et al., 2002; Shah et al., 2008).