Finally, our results indicated that ZINC21710815 induces autophagy in BaF3/WT and BaF3/T315I leukemia cells, based on the increase in the expression of the autophagy-related proteins LC3-II and Beclin1, in BaF3/WT, and BaF3/T315I leukemia cells. Here, BECN1 is linked to leukemia.