Furthermore, the levels of glucose uptake, MMP, total ROS, and intracellular lactate were partially rescued in c-Myc-overexpressing B-ALL cells after treatment with SNS-032 (Figures 6E–I), implying that CDK9i blocked the glycolysis of B-ALL cells by reducing c-Myc expression. Here, MYC is linked to acute lymphoblastic leukemia.