In 4T1 breast cancer mouse model, which is a suitable experimental animal model for human mammary cancer, artemisinin (ART) significantly promotes 4T1 tumor cell apoptosis and decreases TGF-β levels and the numbers of both MDSC and Treg to inhibit tumor growth in mice (Cao Y. et al., 2019) (Figure 4 and Table 4). This evidence concerns the gene TGFB1 and breast cancer.