Both Resveratrol (RSV) and Dendrosomal Curcumin (DNC) are revealed to downregulate the expression levels of IL-10 and Arg1 on TAM through the inactivation of STAT3 to reduce the numbers of TAM, further inhibiting tumor growth and metastasis (Shiri et al., 2015; Sun et al., 2017) (Table 4). The gene discussed is STAT3; the disease is neoplasm.