Using proximity-dependent biotin identification (BioID) and Strep-Tactin pulldown assays, IFT20 was found to participate in the vesicular transport of Numb and Ctnnal1 from the trans-Golgi/TGN to the plasma membrane; moreover, both IFT20 interactors inhibited breast cancer cell migration. The gene discussed is CTNNAL1; the disease is breast carcinoma.