IFT70B and ciliopathy: CCP5 acts downstream of Fleer/IFT70 for tubulin deglutamylation, which halts ciliogenesis in zebrafish; Moreover, hyperglutamylation of axonemal microtubules in pronephric cilia induced by CCP5 deficiency also leads to motility defects and ciliopathy phenotypes (Pathak et al., 2014).