Alzheimer’s disease is the most common neurodegenerative disease in the world and is characterized by the accumulation of beta-amyloid (Aβ) plaques from amyloid precursor protein (APP) and hyperphosphorylated tau protein (Iqbal et al., 2010; Murphy and Levine, 2010). The gene discussed is APP; the disease is early-onset autosomal dominant Alzheimer disease.