CEACAM5 and metastatic malignant neoplasm in the lymph nodes: STAS was more likely to be observed in patients with no smoking history (P = 0.049), elevated carcinoembryonic antigen (CEA) level (P < 0.001), ADC (P < 0.001), lymph node metastasis (P < 0.001) and high pathologic TNM stage (P < 0.001) (Table 1).