The median EMP1 mRNA level was lower in patients with E2A-PBX1 as compared to other cytogenetic subtypes of B-ALL (BCR-ABL1 p=0.004; hyperdiploidy p=0.0056; ETV6-RUNX1 p=0.0046; hypodiploidy p=0.033 and B-others p=0.0026) and controls (p=0.013). This evidence concerns the gene PBX1 and acute lymphoblastic leukemia.