S100P and digestive system cancer: Furthermore, high S100P expression was significantly associated with distant metastasis (OR=3.58, P=0.044), advanced clinical stage (OR=2.03, P=0.041) and recurrence (OR=1.66, P=0.007).<h4>Conclusion</h4>S100P might act as a prognostic indicator of non-gastrointestinal tract cancers.