Multivariate cox regression indicated that NOS3 expression (HR = 2.416, 95% CI: 1.181–4.941, p = 0.016) and tumor stage (HR = 5.101, 95% CI: 2.353–11.058, p < 0.001) were independent prognostic factors for OS (Figure 5C). The gene discussed is NOS3; the disease is neoplasm.