According to the expression levels of estrogen receptor [ER], progesterone receptor [PR], and human epidermal growth factor receptor 2 [HER2] protein, breast cancer can be divided into four subtypes: luminal -A, luminal-B, HER-2 positive, and triple negative breast cancer (TNBC) (2, 3). This evidence concerns the gene ERBB2 and triple-negative breast carcinoma.