According to GSEA, the high HOTAIR, SOX21-AS1, and STEAP3-AS1 expression groups are mainly enriched in pathways related to cancer, including apoptosis, ECM receptor interaction, focal adhesion, the JAK-STAT signaling pathway, cancer, cell cycle, cancer, the calcium signaling pathway, and the MAPK signaling pathway (Figures 8C, F, I, Supplementary Table 2). The gene discussed is HOTAIR; the disease is cancer.