The results showed that classifications of Child–Pugh, BCLC, TNM, Okuda and CLIP, as well as tumor size, PVTT, invasion of adjacent tissues, microvascular invasion, intrahepatic transfer, tumor grade, prothrombin time, and levels of fibrinogen, albumin, total bilirubin, total cholesterol, ALT and GGT were significant indicators of OS. This evidence concerns the gene F2 and neoplasm.