WT1 and leukemia: The Wilms tumor 1 (WT-1) locus in chromosomal region 11p13; encodes a transcription factor highly expressed in the cells of the majority of leukemia patients at diagnosis, and apparently participates in leukemogenesis.5 High expression of WT-1 in acute leukemia has been reported to represent a molecular marker of malignant hematopoiesis and was associated with fewer remissions and poor overall survival.6,7