Thus, it has a good immunosuppressive action in some diseases like rheumatoid arthritis.12 There is some evidence that it can be used as an immune-modulator in preventing and reversing the depigmentation of vitiligo lesions in mouse model owing to the inhibitory effects of simvastatin on STAT1.5 Therefore, there have been suggestions that it can be used as a treatment in vitiligo patients. Here, STAT1 is linked to vitiligo.