Moreover, higher amounts of TILs with the expression of CD8+/CD69+/CD25‐ in ex tumor slices were further visualized in the mice treated by the combinational strategy through immunofluorescent staining and immunohistochemical analysis (Figure 5J and Figure S16, Supporting Information); meanwhile, the cancer cell killing effects were further confirmed by TUNEL staining (Figure 5K). The gene discussed is CD69; the disease is cancer.