The oncofetal mRNA‐binding protein IGF2BP1 has the most conserved “oncogenic” role of the IGF2BP family in tumor‐derived cells,[20] promoting a mesenchymal tumor cell phenotype characterized by elevated proliferation, migration, and invasion.[21, 22, 23] Given that PADI2 regulates IGF2BP1 expression in EC cells, it is possible that depletion of IGF2BP1 may have the same effect on inhibiting EC cell progression as that of PADI2 knockdown. The gene discussed is PADI2; the disease is neoplasm.