SOX2 and colorectal carcinoma: Our finding is in line with other reports showing that IGF2BP1 can inhibit mRNA decay and promote translation by binding to m6A modification of several target transcripts,[22, 33, 53, 56] thus confirming IGF2BP1 as a m6A‐reader for SOX2. It is worth noting that IGF2BP2, the other IGF2BP family member, has also been shown to bind to SOX2 and prevent SOX2 mRNA degradation via an m6A‐dependent manner in colorectal carcinoma, to preserve the tumor stemness phenotype.