A possible mechanism to explain PD‐L1 expression by p62/SQSTM1 in gastric cancer has been the demonstration of NF‐κB activation, which impacts the PD‐L1 promoter.[23] We confirmed that that IRIN treatment can induce the phosphorylation of the p65 (p‐p65) subunit of NF‐κB in KPC cells (Figure S4, Supporting Information). This evidence concerns the gene CD274 and gastric cancer.