CD274 and gastric cancer: Of specific importance to the objective of addressing IRIN immunogenicity, it has recently been demonstrated that the accumulation of p62/SQSTM1 during pharmacological disruption of autophagy can trigger PD‐L1 expression in gastric cancer cells.[23] Not only did we demonstrate IRIN treatment can induce robust cell surface expression of PD‐L1 in KPC cells during the performance of confocal microscopy (Figure 1E, bottom right panel), but also observed the same effect during immunoblotting (Figure 1F).