Accordingly, 83 genes encoding for pivotal effectors in cellular allostasis and homeostasis, such as homeotic genes of HOXA and HOXB clusters, PAX6 and PAXIP1, and 64 genes involved in the retinoid metabolism and liver specification, such as ALDH1A2, ALDH1A3, RARB, RXRB, and RXRG, were differentially expressed in Peruvian HCC [36]. The gene discussed is PAX6; the disease is hepatocellular carcinoma.