PRDX1 and metastatic malignant neoplasm in the lymph nodes: However, PRDX1 expression was not related to age (OR = 0.99, 95% CI: 0.73-1.36, P = 0.966, random effects), gender (OR = 0.93, 95% CI: 0.74-1.17, P = 0.514, fixed effects), depth of invasion (OR = 1.11, 95% CI: 0.37-3.38, P = 0.854, random effects), lymph node metastasis (OR = 1.47, 95% CI: 0.93–2.34, P = 0.100, random effects), and distant metastasis (OR = 1.94, 95% CI: 0.84-4.47, P = 0.120, fixed effects).