Moreover, PRDX1 overexpression had a significant association with advanced TNM stage (OR = 2.26, 95% CI: 1.24-4.13, P = 0.008, random effects) and poor tumor differentiation (OR = 0.59, 95% CI: 0.44-0.81, P = 0.001, fixed effects). The gene discussed is PRDX1; the disease is neoplasm.