In addition to the signaling pathways mentioned above, those related to PRDX1 are involved in the p53 signaling pathway, Akt/mTOR signaling pathway, PI3K/Akt signaling pathway, pathways in cancer, FoxO signaling pathway, cell cycle, and ubiquitin-mediated proteolysis [8, 20, 44]. The gene discussed is TP53; the disease is cancer.