Rusk et al. (91) also noted a lack of IL-22 expression by T cells within late-stage granulomas from lung and mediastinal lymph nodes, confirmed by Palmer et al. (93) who observed very low expression levels of IL-22 in lymph nodes with advanced granulomatous lesions, i.e., samples collected at ±21 WPI, with no differences in expression between granulomatous and uninfected lymph nodes. The gene discussed is IL22; the disease is Granuloma.