SNP was responsible for most variants, and single nucleotide variants (SNVs) mostly occurred as C > T and C > A. The top ten mutated genes in ACC samples were TTN, MUC16, PKHD1, TP53, CTNNB1, CNTNAP5, SVEP1, LRP1, HMCN1, and ASXL3 (Figure 7A). This evidence concerns the gene ASXL3 and adrenal cortex carcinoma.