Consistent with our findings, Najm et al. reported decreased miR-17-5p in erosive RA synovial tissue and demonstrated that miR-17 transfection into arthritic paws in a collagen-induced arthritis model reduced inflammation, immune cell infiltration, and structural damage and identified STAT-3 and JAK-1 as targets of miR-17 in RA synovial fibroblasts (60). This evidence concerns the gene STAT3 and rheumatoid arthritis.